However, there are a handful of states that let local jurisdictions not only levy sales taxes, but independently regulate and administrate those sales taxes as well. These are known as "home rule" states. The states that allow total home rule are Alabama, Arizona, Colorado and Louisiana. Not all localities in home rule states take this option, but when they do, they can create sales tax rules and processes that are completely separate from the state's. In Alaska, there is no statewide sales tax, but local jurisdictions can independently levy and collect sales tax according to their own nexus rules.
Home rule can be tricky for online sellers, as each locality can potentially define nexus differently as well as also require a separate registration, filing and payment process.
Take Colorado, for example, the most complex home rule state, with 70 cities that administer their own sales tax. Say you are an online retailer based in Denver (a home rule city). You would have nexus in Colorado as well as in Denver, so if you sell to a customer in Denver, you would need to collect Denver sales tax as well as state sales tax. Although the sales tax would be collected all at once from the customer, you would report and remit the two different sales taxes separately —the city tax to Denver and the state tax to the state. However, if you are based in Denver and have a customer in Boulder, but no nexus in Boulder, you would only need to collect state sales tax on that transaction since the tax is based on the location of the customer.